中文

2024-02-18

前沿速览012期| CAR-T治B淋 前沿览新知


01

针对CD80/86上调的弥漫大B细胞淋巴瘤,一种抗CD19/CTLA-4开关可提高CAR-T细胞的疗效和选择性

An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL


第一作者:Prinz LF


Cell Rep Med (IF=14.3). 2024 Feb 5:101421.


全文网址:https://www.sciencedirect.com/science/article/pii/S2666379124000442

02

双特异性抗体与CAR-T细胞治疗大B细胞淋巴瘤:两种免疫治疗的比较

Bispecific antibodies and CAR-T cells: dueling immunotherapies for large B-cell lymphomas


第一作者:Trabolsi A


Blood Cancer J (IF=12.8). 2024 Feb 8;14(1):27.


全文网址:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10853226/

03

HSP90-MYC-CDK9 网络驱动套细胞淋巴瘤治疗的耐药性

The HSP90-MYC-CDK9 network drives therapeutic resistance in mantle cell lymphoma


第一作者:Yan F


Exp Hematol Oncol (IF=11.4). 2024 Feb 7;13(1):14.  


全文网址:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10848414/

05

CAR-T 细胞治疗后EBV相关淋巴组织增生性疾病

EBV-associated lymphoproliferative disease post-CAR-T cell therapy


第一作者:Zhang S


Front Med (IF=8.1). 2024 Feb 8. 


全文网址:https://journal.hep.com.cn/fmd/EN/10.1007/s11684-023-1032-8

06

单采产品中的单核细胞会影响 CD19 CAR-T 细胞治疗淋巴瘤患者的结局

Monocytes in leukapheresis products affect the outcome of CD19-targeted CAR T-cell therapy in lymphoma patients


第一作者:Carniti C


Blood Adv (IF=7.6). 2024 Feb 15:bloodadvances.2024012563.


全文网址:https://ashpublications.org/bloodadvances/article/doi/10.1182/bloodadvances.2024012563/514980/Monocytes-in-leukapheresis-products-affect-the

07

在ZUMA-7研究中,二线axicabtagene ciloleucel或标准方案治疗后的后续抗淋巴瘤治疗结局

Outcomes of subsequent anti-lymphoma therapies after second-line axicabtagene ciloleucel or standard of care in ZUMA-7


第一作者:Ghobadi A


Blood Adv (IF=7.6). 2024 Feb 5:bloodadvances.2023011532. 


全文网址:https://ashpublications.org/bloodadvances/article/doi/10.1182/bloodadvances.2023011532/514814/Outcomes-of-subsequent-anti-lymphoma-therapies

08

简要研究报告:深入的免疫分型揭示CD19 CAR-T细胞随时间变化的稳定性

Brief research report: in-depth immunophenotyping reveals stability of CD19 CAR T-cells over time

第一作者:Odak I


Front Immunol (IF=7.3). 2024 Jan 22;15:1298598. 


全文网址:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10839090/

09

CD19 CAR-T细胞治疗继发性中枢神经系统淋巴瘤

Treatment of secondary CNS lymphoma using CD19-targeted chimeric antigen receptor (CAR) T cells


第一作者:Kline K


Cancer Immunol Immunother (IF=5.8). 2024 Feb 13;73(3):45.


全文网址:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10864416/

10

CAR-T细胞治疗在中枢神经系统淋巴瘤中的持续疗效:个体数据的系统评价和荟萃分析

Sustained efficacy of chimeric antigen receptor T-cell therapy in central nervous system lymphoma: a systematic review and meta-analysis of individual data


第一作者:Zhou J


Front Pharmacol (IF=5.6). 2024 Jan 24;14:1331844. 


全文网址:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10847290/

10

标准治疗方案治疗复发/难治性弥漫大B细胞淋巴瘤的结局:真实世界数据分析

Treatment Outcomes with Standard of Care in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Real-World Data Analysis


第一作者:Ip A


Adv Ther. 2024 Feb 2.


全文网址:https://link.springer.com/article/10.1007/s12325-023-02775-9


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审批编号:NP-NHL-2024.2-1 valid until 2026.2


供稿与审核:临床开发与医学部