中文

2024-03-01

前沿速览013期| CAR-T治B淋 前沿览新知


01

BTK抑制剂是否能改善CAR-T细胞治疗套细胞淋巴瘤的疗效?

Does BTKi improve CAR T-cell therapy in MCL?


第一作者:Boardman AP


Blood (IF=20.3). 2024 Feb 22;143(8):653-655.


全文网址:https://ashpublications.org/blood/article/143/8/653/514999/Does-BTKi-improve-CAR-T-cell-therapy-in-MCL

02

靶向自噬可克服CAR-T细胞免疫疗法治疗B细胞恶性肿瘤的内在耐药性

Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies


第一作者:Tang L


Cancer Commun (Lond) (IF=16.2). 2024 Feb 26. 


全文网址:https://onlinelibrary.wiley.com/doi/10.1002/cac2.12525

03

视频教育对CAR-T细胞疗法受试者影响的探索性随机对照试验

Pilot Randomized Controlled Trial of an Educational Video for CAR T-Cell Therapy Recipients


第一作者:Johnson PC


J Natl Compr Canc Netw (IF=13.4). 2024 Feb 27:1-8.  


全文网址:https://jnccn.org/view/journals/jnccn/aop/article-10.6004-jnccn.2024.70011/article-10.6004-jnccn.2024.70011.xml

04

淋巴瘤患者在接受Axi-cel治疗前的桥接治疗

Bridging therapy before axi-cel for lymphoma


第一作者:Belbachir S


Blood Adv (IF=7.6). 2024 Feb 27;8(4):1051-1052. 


全文网址:https://ashpublications.org/bloodadvances/article/8/4/1051/515007/Bridging-therapy-before-axi-cel-for-lymphoma

05

多靶点CAR-T在治疗B细胞恶性肿瘤中的作用

The role of chimeric antigen receptor T cells targeting more than one antigen in the treatment of B-cell malignancies


第一作者:Brillembourg H


Br J Haematol (IF=6.5). 2024 Feb 16. 


全文网址:https://onlinelibrary.wiley.com/doi/10.1111/bjh.19348

06

基于慢病毒载体的一种新型方法生产靶向Aspergillus fumigatus的CAR-T细胞

A novel lentiviral vector-based approach to generate chimeric antigen receptor T cells targeting Aspergillus fumigatus


第一作者:Kumaresan PR


mBio (IF=6.4). 2024 Feb 28:e0341323. 


全文网址:https://journals.asm.org/doi/10.1128/mbio.03413-23

07

利用单细胞测序技术揭示CAR-T细胞和白血病/淋巴瘤的转录特征

Harnessing the Transcriptional Signatures of CAR-T-Cells and Leukemia/Lymphoma Using Single-Cell Sequencing Technologies

第一作者:Liao YM


Int J Mol Sci (IF=5.6). 2024 Feb 19;25(4):2416. 


全文网址:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10889174/

08

自体干细胞移植联合CAR-T细胞治疗难治/复发B细胞非霍奇金淋巴瘤患者前,BEAM方案与BEAMF方案的预后差异

Prognostic differences between carmustine, etoposide, cytarabine and melphalan (BEAM) and carmustine, etoposide, cytarabine, melphalan and fludarabine (BEAMF) regimens before autologous stem cell transplantation plus chimeric antigen receptor T therapy in patients with refractory/relapsed B-cell non-Hodgkin-lymphoma


第一作者:Xin X


Cytotherapy (IF=4.5). 2024 Feb 19:S1465-3249(24)00044-6. 


全文网址:https://www.sciencedirect.com/science/article/pii/S1465324924000446

09

CAR-T治疗老年患者的临床效果和安全性

Clinical Outcomes and Toxicity in Older Adults Receiving Chimeric Antigen Receptor T-cell Therapy


第一作者:Johnson PC


Transplant Cell Ther (IF=3.2). 2024 Feb 25:S2666-6367(24)00225-2.  


全文网址:https://www.sciencedirect.com/science/article/abs/pii/S2666636724002252

10

ZUMA-5(Axicabtagene Ciloleucel)与SCHOLAR-5研究中复发/难治性滤泡性淋巴瘤患者的3年随访结局比较

A Comparison of 3-Year Follow-up of ZUMA-5 (Axicabtagene Ciloleucel) With SCHOLAR-5 in Relapsed/Refractory Follicular Lymphoma


第一作者:Ghione P


Clin Lymphoma Myeloma Leuk (IF=2.7). 2024 Jan 24:S2152-2650(24)00055-7.


全文网址:https://www.clinical-lymphoma-myeloma-leukemia.com/article/S2152-2650(24)00055-7/abstract?uuid=uuid%3Ab70c4f71-6143-42a0-902e-3d3d46bb2bf2


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审批编号:NP-NHL-2024.3-1 valid until 2026.3


供稿与审核:临床开发与医学部